E2B

E2BSince 2023-04

E2B provides secure, sandboxed cloud execution environments where AI agents can run code, access files, and interact with tools without risking host systems. It offers SDKs in Python and JavaScript for spinning up isolated compute sandboxes in milliseconds. The platform is designed specifically for agent builders who need safe code execution capabilities.

E2B (formerly known as a sandbox infrastructure startup) focuses on the execution layer for AI agents. Their sandboxes support any language and can be customized with pre-installed packages.

AgnoSince 2025-10

Agno (formerly Phidata) is a lightweight, ultra-fast Python framework engineered for building production-grade autonomous multi-agent systems with native memory, knowledge retrieval, and multimodal reasoning capabilities. It is designed to replace bloated agent frameworks with a pure, pythonic developer experience. Agno agents operate up to 10x faster than legacy orchestration libraries by eliminating unnecessary abstractions. With built-in support for vector databases (PgVector, Qdrant, Pinecone), structured output schemas, and agent-to-agent delegating protocols, developers can build complex autonomous assistants with under 20 lines of clean code.

The framework includes first-class multimodal tools allowing agents to analyze images, process video streams, execute code in secure sandboxes, and query SQL databases. Agno agents natively persist session state and user memory in PostgreSQL, making stateful conversations effortless across web sessions. Agno is fully open-source with extensive documentation, offering enterprise-ready middleware for authentication, telemetry, and rate limiting.